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Funding This trial was supported by Novo Nordisk A/S, Denmark
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In an older study from 2002 in 108 fertile and 103 subfertile men, taking 5 mg of folic acid and 66 mg of zinc daily for 6 months increased sperm count by 74% in the subfertile group ( A review of 7 controlled trial studies in subfertile men also found that those who took a daily folate and zinc supplement had a significantly higher sperm concentration, as well as much higher quality sperm, than those taking a placebo ( Similarly, a 6-month study in 64 men with infertility found that those who took a daily supplement containing vitamin E, selenium, and folate had a significantly higher sperm count and more motile sperm than those who took a placebo ( However, other studies have found that folate and zinc have no effect on male fertility and conception
These drugs are a promising addition to the mix
On the other hand, GPx (a selenoenzyme) can decompose H 2 O 2 as well as other organic peroxides and requires GSH
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