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Concentrations of guanidinoacetate in the pancreas of Phase-II HSB were elevated ( P 0.05) in pancreatic creatinine concentrations was detected among the three treatment groups
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These modifications make it approximately 3 times more potent and extend its half-life (20-30 hours) and duration of action
The first step was designing an analogue of a biological medicine - a hormone called GLP-1, used in treatments for type 2 diabetes and obesity - that was inherently more stable in the harsh environment of the stomach
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