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Curr Protoc Mouse Biol , 2020, 10(1): e68
Size-exclusion chromatography addresses aggregate state
& Kashiwagi, K
At the intranasal doses used in Schneider-Helmert's human protocols (roughly 25 to 30 nmol/kg), the resulting total dose for an average adult falls in the low-to-mid microgram range, substantially less than the milligram-level doses commonly sold in single vials
It is essential to ensure the treatment is done in a sterile, clinical environment with proper professional oversight
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