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Although sulfa antibiotics saved lives, their use decreased significantly after the introduction of penicillin because of frequent adverse reactions and emerging bacterial resistance

Pediatr Nephrol 25:24592467

Full Video Narration: Does GLP-1/GIP Therapy Cause Muscle Loss

Secondary (Organic) Constipation Dietary: Low fiber, dehydration Medications: Opioids, anticholinergics, calcium channel blockers, iron supplements Metabolic / Endocrine: Hypothyroidism, diabetes mellitus, hypercalcemia Neurological: Parkinsons disease, spinal cord injury, multiple sclerosis Obstruction: Colorectal cancer, strictures, volvulus Psychogenic: Depression, eating disorders Clinical Features Infrequent bowel movements ( 50) Anorectal manometry or transit studies (if chronic functional constipation) Management 1

Reviving a Sluggish Metabolism A sedentary lifestyle makes it easy for metabolism to go quiet, turning calories into storage instead of fuel