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However, the trend has also been linked to a reduction in behavioural health interventions , which raises significant clinical concerns

Exclusion criteria were a history of bariatric surgery, alcohol use disorder identification test (AUDIT) greater than 16, hemoglobin A1c measurement greater than 9, a history of seizure disorder or traumatic brain injury, on specific medications that interfere with alcohol metabolism such as certain antibiotics (reviewed on a case-by-case basis by study physician), or currently pregnant or lactating

A lot of these side effects can be avoided by starting at the lowest dose, 8 milligrams, and gradually increasing it, Lazarus says

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