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Niacin, particularly at pharmacologic doses, can impair insulin sensitivity and increase hepatic glucose production, potentially raising blood glucose levels
Hindbrain nucleus tractus solitarius glucagon-like peptide-1 receptor signaling reduces appetitive and motivational aspects of feeding
Two primary strategies to enhance incretin receptor signaling have been explored for type 2 diabetes treatment
Nauck MA et al
38,7 (2015): e98-9
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