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Journal of Pediatric Endocrinology and Metabolism , 22(11), 10531061
Agonistas del receptor del GLP-1: clasificacin y evidencia clnica de la eficacia hipoglucemiante El primer agonista del receptor de GLP-1 fue la exendina-4, pptido natural de 39 aminocidos aislado de secreciones salivales del reptil Heloderma suspectum con un secuencia homloga del 53% del pptido nativo
vehicle-injected PNA mice, which displayed clear signs of altered cyclicity, denoted by the presence of only one generation of corpora lutea, frequently corresponding to persistent regressing corpora lutea, indicative of occasional ovulations
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