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Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death
December 2016.
The prooxidant oxidative stress imbalance needs an antioxidant system able to balance it and the principal role in antioxidant defense is carried out by antioxidant enzymes, with the paramount involvement of small-molecule antioxidant compounds like GSH
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The intrinsic apoptotic pathway responds to intracellular signals such as DNA damage or oxidative stress
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