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Zhang X, Selvaraju K, Saei AA, DArcy P, Zubarev RA, Arner ES, Linder S (2019) Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug
It declines with age, and lower NAD+ is associated with slower metabolism and the changes we lump together as getting older. NNMT, meanwhile, consumes the raw materials your body uses to make NAD+ and in fat tissue, NNMT is often overexpressed, which can drag NAD+ down right where you least want a sluggish metabolism
doi: 10.1007/s42729-021-00532-x 109 VijayarenganP.MahalakshmiG
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