That extended window means it can drive sustained muscle protein synthesis, satellite cell activation, and nutrient partitioning in a way that short-acting IGF-1 simply can't
Tirzepatide is a novel agent that acts as an agonist for both GLP-1 receptors and gastric inhibitory polypeptide (GIP) receptors, another incretin that lowers glucose and appetite
While GLP-1 agonists are generally well-tolerated, there are certain contraindications and precautions to consider, such as: History of pancreatitis, diabetic retinopathy, thyroid cancer
Research also suggests that GLP-1 medications may help restore ovulation in women with PCOS who aren't ovulating regularly, though this area needs more study
As more people experience reduced hunger and smaller portions on these medications, they also begin looking for solutions that feel less invasive or more affordable