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The aim of this study is to assess PE-A5% as a treatment for patients with ACLF in a pivotal study Methods: A phase 3, multicenter, randomized (1:1), controlled, parallel-group, open-label study (APACHE) compares standard medical treatment (SMT) + PE-A5% (treatment arm) to SMT alone (control arm)
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In the SURMOUNT-1 trial, patients lost an average of 15-21% of their initial body weight over 72 weeks, with results varying by dose and individual factors
JJH is a minority shareholder and board member of Antag Therapeutics and Bainan Biotech and has been a consultant for, has served on scientific advisory panels of, and has been speaker honoraria for Novo Nordisk and MSD/Merck
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