Historical concerns about GLP-1s and cancer Early worries about GLP-1 medications and cancer began in 2009 when reports from the US Food and Drug Administrations database suggested possible links between the first GLP-1 drugs and thyroid and pancreatic cancers
demonstrated that complete signal recovery requires either a twopathway network architecture or druginduced target dimerization
WalrabensteinWWagenaarCAvan de PutMvan der LeedenMGerritsenMTwiskJWRet al
Recommended screening tests may include complete blood count, comprehensive metabolic panel, iron studies (ferritin, serum iron, TIBC, transferrin saturation), thyroid function tests (TSH, free T4), vitamin B12 (especially in patients taking metformin), vitamin D levels, and potentially other assessments based on clinical suspicion
While B12 injections can benefit virtually anyone, there are certain groups of people who are more likely to experience deficiencies and may benefit the most from these injections