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Moderate weight loss is sufficient to affect thyroid hormone homeostasis and inhibit its peripheral conversion

Anyone using a compounded GLP-1 medication should work with a licensed provider who understands the sourcing, dosing, and monitoring involved

Using them may promote mild weight loss results

Winning will require both safety and efficacy The next wave of competition will not be driven by efficacy alone

Diana Mesa, RDN, LDN, CDCES, founder of En La Mesa Nutrition, agrees, adding that Berberine does have some similarities [to GLP-1 RA medications] in that it can trigger the pancreas to release insulin and helps make cells more sensitive to the effect of insulin, which is a characteristic similar to what Metformin [another prescription medication prescribed to treat type 2 diabetes and other off-label conditions] does. Still, she notes that its unclear whether or not Berberine has any appetite-suppressing effects like Ozempic and similar medications