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A diet high in protein and fiber coupled with ample hydration and consistent resistance training is crucial." Semaglutide is also available with a higher dose (2.4 mg) in the drug Wegovy, which is FDA-approved for weight loss

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A systematic review of osteoarthritis clinical practice guidelines found that most guidelines for knee and hip OA recommend weight loss for patients with overweight or obesity, but very few specify how weight management should be operationalized in practice

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