For most adults, 500 calories a day is very low and is usually not enough to support energy, protein needs, muscle preservation, digestion, or daily function
N Engl J Med 389:514526 Jerlhag E (2023) The therapeutic potential of glucagon-like peptide-1 for persons with addictions based on findings from preclinical and clinical studies
48 KoizumiS.YonetaniY.MaruyamaA.TeshibaS
Individual variation is high and depends on your baseline metabolism, starting weight, and genetic factors
Originally developed to help patients manage type 2 diabetes, semaglutide gained widespread attention when studies showed it could help individuals lose a significant amount of weight by reducing hunger, slowing gastric emptying, and helping people feel full for longer periods