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Browning MG, Pessoa BM, Khoraki J, et al
Semaglutide targets the GLP-1 receptor, while tirzepatide functions as a dual GLP-1 GIP receptor agonist, activating both GLP-1 and GIP pathways
The only difference is what they're FDA-approved to treat: Zepbound for weight loss, Mounjaro for type 2 diabetes
Trying to restart at your previous therapeutic dose would likely cause significant side effects similar to starting at a high dose initially
They aim to mimic the effects of the glucagon-like peptide 1 (GLP-1) hormone, a naturally produced hormone which helps regulate your appetite and blood sugar levels
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