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Clinical dose-finding work with estradiol matrix systems showed that even the 0.025 mg/day patch significantly reduced hot-flash frequency, though higher dosages produced incremental benefit
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Persico, Marco, Raffaele Sessa, Elena Cesaro, Irene Dini, Paola Costanzo, Alberto Ritieni, Caterina Fattorusso, and Michela Grosso
Manufacturing for the future The company highlighted that it has committed over $16 billion to develop new manufacturing sites in the US and Europe since 2020, including in a biologic facility in Limerick, Ireland