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In fact, in the context of IBD, inducing such an M2 macrophage skew via PDEVs correlates with enhanced resolution of colitis: for instance, GsDEVs treatment in mice with colitis increased IL-10 release from intestinal macrophages, which in turn helped quell intestinal inflammation [133]
Male infertility and reduced life expectancy: epidemiology, mechanisms, and clinical implications
2018;33:292308 e297
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