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Cellular GSSG accumulation is limited by the fact that cells employ multiple redundant reductive pathways to reduce cytosolic GSSG or to actively export GSSG to the extracellular environment, for example by MRP1 in mammalian cells or to alternative subcellular compartments, for example by Ycf1 in yeast 21,69
Stem Cells Int (2017) 2017:7428316
Related upstream secretagogues studied in this space include Tesamorelin and Sermorelin
Localization of excitatory amino acid transporters EAAT1 and EAAT2 in human postmortem cortex: a light and electron microscopic study
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