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2022;34(9):1234e12479
CagriSema 2.4 mg / 2.4 mg demonstrated 22.7% mean weight reduction in adults with overweight or obesity in REDEFINE 1, published in NEJM
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In human AML stem cells, BCAT1 is overexpressed, and the BCAA pathway is activated by the low levels of -KG, displaying a DNA hypermethylation phenotype similar to IDH mutant-positive cancers (Raffel et al., 2017)
10.1186/s12958-021-00765-6 95 OwensL
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