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Although postoral glucose tolerance test glucose levels were unaffected, the AGM intervention significantly reduced fasting insulin levels and HOMA-IR, indicating improved insulin sensitivity compared with placebo
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Additionally, the administration of oral GLP-1 drugs requires strict guidance: for example, semaglutide must be taken on an empty stomach in the morning, with no more than 120 mL of water, and patients must wait at least 30 minutes before having breakfast
