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P.HamdaneM.et al (2006)
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It circulates at relatively high concentrations when you're young, around 200 ng/mL in your 20s , and drops steadily with age, reaching roughly 80 ng/mL by your 60s
And critically, it acts on the hypothalamus to reduce appetite, creating powerful satiety signals that make people eat significantly less without feeling deprived
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PubMed Brzoska T, et al
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