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The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)

[110] Animals can convert cyanocobalamin and hydroxocobalamin to the bioactive forms adenosylcobalamin and methylcobalamin by enzymatically replacing the cyano or hydroxyl groups

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