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In a head-to-head trial published in the New England Journal of Medicine in May 2025, Mounjaro users lost 20.2 percent of body weight compared to 13.7 percent for Wegovy users
However, the study authors highlight that further research is necessary, as its unclear whether the increased dietary restraint that GLP-1s may contribute to is helpful for self-control or may instead lead to imbalanced forms of restricted eating, such as skipping meals
Other lipotropic injection side effects include: Headaches and light headedness Stomach upsets such as mild nausea and mild diarrhea Allergic reactions (itching, hives, shortness of breath, wheezing, swelling of the tongue, throat, or mouth) although rare, can also occur
Compounded versions are cheaper and more available
Why it matters for longevity Living longer is only part of the goal
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