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FIGURE 5 3.6 Liver-specific GPX4 knockdown abrogates the protective effect of TA against APAP-induced hepatocyte apoptosis To further investigate the role of liver-specific GPX4 knockdown in the protective effects of TA against APAP-induced apoptosis, we analyzed the expression of key pro-apoptotic and anti-apoptotic proteins in the APAP + TA and APAP + TA + GPX4 KD groups

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