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Pica test serves as an indirect indicator of nausea/malaise in non-vomiting species (e.g., mice), assessed through the ingestion of kaolin clay, a non-nutritive substance that mice instinctively consume as a response to gastrointestinal discomfort 77

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Therefore, mitochondria-associated synaptic abnormalities are likely to contain robust therapeutic targets for ASD that have yet to be discovered

Glucagon receptor activation increases energy expenditure and may promote hepatic fat reduction, which could offer additional benefits for conditions such as metabolic dysfunction-associated steatotic liver disease (MASLD, previously known as NAFLD)

On the inner mitochondrial membrane, CPTII (carnitine-palmitoyl transferase II) catalyzes the transfer of fatty acids from L-carnitine to free CoA