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The metabolism of homocysteine involves three pivotal processes: S-adenosyl-l-methionine (SAM)-dependent transmethylation, folate-dependent or -independent remethylation cycles, and transsulfuration reactions

Stepanova, Y.N

Methods Enzymol 1(541):310 Lawrence RA, Burk RF (1976) Glutathione peroxidase activity in selenium-deficient rat liver

Furthermore, many compounds are potential candidate drugs for cancer treatment by regulating PCD, most of them are currently based on experiments in cells and mice, and there is a lack of clinical research evaluating the clinical effects of such compounds

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