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The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells
This would be expected to have an effect on the rates amino-acid-requiring processes of one-carbon metabolism and glutathione synthesis
These are not minor protocol deviations
Ultimately, determining how elevated GSSG outside the ER leads to a more oxidizing ER lumen will require compartment-specific monitoring and manipulation of the glutathione redox state
Collagen and elastin, the proteins responsible for skin tone and firmness, require synthesis stimulation that the body may not provide at an adequate rate on its own, particularly when caloric intake is suppressed
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