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To further interrogate the underlying dynamics of the Cagri-AMY 3 R complex, relative to rAmy-AMY 3 R complex, we performed molecular dynamics (MD) simulations of Cagri:AMY 3 R:G s and rAmy:AMY 3 R:G s (each system in triplicate, for a total of 6 s)
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doi: 10.1038/leu.2015.174 522 HedgerMPde KretserDM
Figure 1 :Glutathione (GSH) chemical structural formula GSH biosynthesis is directly controlled by its synthetase, rather than as protein synthesis is conducted on the ribosome, glutathione biosynthesis includes the following two reaction, as shown in figure 2
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