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Of the numerous prospective randomized clinical trials evaluating the influence of GLP-1 RA use on cardiovascular outcomes (Table 1), only the ELIXA study of lixisenatide [28] has thus far published its results

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The international or national clinical trial registries, including the ClinicalTrials.gov, European Union Clinical Trials Register, World Health Organization-International Clinical Trials Registry Platform and 9 national clinical trial registries were also searched

B12 is essential for healthy blood cell production, energy levels, neurotransmitter production, and many other bodily processes

Insulin Secretion (Glucose-Dependent): GLP-1 agonists stimulate the pancreas to release insulin only when blood sugar is high, lowering the risk of severe low blood sugar (hypoglycemia) compared to some other diabetes meds