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The chronic subcutaneous administration of Ex-4 attenuates the peripheral symptoms of type 2 diabetes in rats, including hyperglycemia and IR, and enhances the levels of brain cortical GLP-1 and insulin-like growth factor (IGF)-1 and their downstream signaling pathways

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Textural properties like specific surface area, porosity, pore size, and particle size are relevant for the bioactivity of biomaterials such as the biogenic SiNPs from RH in our case

Knoops et al., 2016)

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