Strikingly, GGCT-mutant cells effectively counteracted this metabolic augmentation, rescuing the levels of key intermediates including pyruvate, succinate, and fumarate (Fig
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applied proximity labeling techniques to zebrafish and designed the bait protein lamin A (LMNA) and the negative control GFP (green fluorescent protein) to establish TurboID and miniTurbo labeling in early zebrafish embryos and optimized and compared them
Scheerer et al., 2007) using the binding site detection program CAVITY (Yuan et al., 2011, 2013) and the allosteric site motion correlation analysis program CorrSite (Ma et al., 2016)