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This timeline aligns with the body's natural metabolic adaptation process and allows for proper nutrient absorption and utilization
But robust human clinical evidence specifically for disc herniations is still developing
After infusion of 18 F-labeled fluorodeoxyglucose ( 18 F-FDG), which is a non-metabolisable glucose analogue, into the intestinal lumen and sealing of the compartment system through surgery, PET-CT imaging showed accumulation of 18 F-FDG in the intestinal lumen of diabetic rats receiving a single oral dose of metformin (Zubiaga et al., 2023)
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