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[published online: May 30, 2019]
Stabilization of -catenin by genetic defects in melanoma cell lines
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SAG S-acetyl-glutathione a method for increasing circulating and/or intracellular levels of glutathione comprises orally administering to an individual in need thereof a delayed-release, gastro-resistant capsule which contains an amount of S-acetyl-glutathione (SAG) effective to increasing circulating and/or intracellular levels of glutathione
In hepatocellular carcinoma, PRMT1 catalyzes the methylation of PHGDH at residue R236 to enhance its enzymatic activity ( The tumor classification based on SSP activation patterns reveals that the conserved mechanisms of SSP, including redox homeostasis maintenance, one-carbon metabolism and drug resistance regulation, can serve as universal targets for pan-cancer therapeutic interventions
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