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The glutathione-binding site in glutathione S-transferases
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A 1987 study on mice determined oral glutathione to be nontoxic,27 and a 2017 toxicity study (also on mice) found that glutathione's LD (the amount of a substance needed to kill 50% of all test animals in one dose) was 5g/kg.6 An equivalent toxic dose for an 80kg human would be 32.5g, which is more than 32 times the highest amounts used in clinical studies
Interestingly, intravenous injections of glutathione have been used for years but there is not even a single clinical trial evaluating its efficacy
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