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References 1 AitkenRJSmithTBJoblingMSBakerMADe IuliisGN

The gap between those two figures is where most unpleasant surprises live

60% of participants achieved 20% or more weight loss -- a threshold historically associated with bariatric surgery outcomes

Additionally, hypoglycaemia (low blood sugar), though less common with GLP-1 agonists than with insulin or sulphonylureas, can cause irritability, confusion, and mood changes when it does occur, particularly in patients taking concurrent diabetes medications

In the context of bulimia nervosa treatment, fluoxetine may help normalise eating patterns, which can also affect weight