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Prescription records showing at least 90 consecutive days of metformin at 1,500 mg daily Documented A1C reduction of less than 1.0% during metformin trial, or Documented intolerance to metformin (GI side effects preventing adherence) Criterion 3: BMI and cardiovascular risk documentation (required in 18 states)

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Out of this study came information that suggested that a significant proportion of the population that included disproportionally the aged, may not be receiving sufficient sulfur and that these dietary supplements, were very likely exhibiting their pharmacological actions by supplying inorganic sulfur

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Evidence Based Women's Health Journal