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Reaney, M
The primary mechanism of action involves: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps lower blood sugar levels without causing hypoglycaemia when glucose levels are normal [3] [4] Suppressing glucagon release , thereby reducing glucose production by the liver Slowing gastric emptying , which prolongs the feeling of fullness after meals Acting on appetite centres in the brain , particularly the hypothalamus, to reduce hunger and food intake When administered as medication, GLP-1 receptor agonists mimic these natural effects but with enhanced duration and potency
About four in ten adults ages 50 to 64 and 65 and older say they have heard a lot about GLP-1 drugs, compared to about one-third of adults ages 30-49 (32%) and one in six adults ages 18-29 (17%)
Epub 2017 Jul 5 29 JefferyP
While the results so far are encouraging, the use of cagrilintide for weight loss is still being studied and isn't yet FDA approved
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