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With both compounds reducing energy intake (tirzepatide through appetite) and mobilizing stored energy (AOD 9604 through lipolysis), the body is working harder to maintain homeostasis
The lower amount is meant to make it easier to track tolerance before changing the plan
AOD-9604 is not believed to have significant direct effects on digestion
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Effect on the gut microbiome: Studies in mouse models show that 5-Amino-1MQ, when combined with diet, affects the gut microbiome, which may have long-term metabolic effects
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