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The barrel width falls between the other two sizes, offering a reasonable balance of capacity and readability

10.1111/j.1463-1326.2009.01158.x 63

5 Conclusions While icodec pharmacokinetics and semaglutide total exposure were unaffected by the combination of icodec and semaglutide in IcoSema, the maximum concentration of semaglutide was higher and occurred earlier presumably owing to icodec outcompeting semaglutide for albumin binding locally at the injection site