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There was significant correlation between the MDASI-Interference items of general activity (est = -0.0063, p = 0.0051), work (est = -0.0059, p = 0.0140), walking (est = -0.0055, p = 0.0084), and enjoyment of life (est = -0.0058, p = 0.0155) with 6MW distance overtime
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N-terminally truncated GLP-1 and exendin-4 peptides lacking the first 8 amino acids (GLP-1(1536) and exendin(939)), exhibit similar affinities in published studies 31 , to their corresponding full-length peptides in the absence of G protein, providing further support that the influence of G s on peptide affinity is predominantly related to interactions of the N-terminus with the TMD
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