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It also opens the door to potential treatment strategies borrowed from psychiatry, where providers have developed protocols for managing SSRI-related sexual side effects over decades

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The Bowers and colleagues canonical work across the 1980s and 1990s reported that co-administration of a GHRH-R agonist with a GHRP-class agent produced greater growth hormone release than either compound alone in healthy human volunteers, with the synergy mechanism interpreted as pulse-amplitude (GHRH-R) versus basal-frequency (GHS-R1a) control of pituitary somatotroph release plus differential engagement of the somatostatin tone [5]

Although not approved for medical use, data from animal and in vitro studies indicate that GLP2-Ts dual-agonist profile may offer advantages over GLP-1only analogs