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Global assessment of the evidence The Modified Bradford Hill Criteria was used to assess the potential relationships among various available evidence [33,34,35]

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Ozempic (which is prescribed to treat type 2 diabetes but can also be taken off-label to aid with weight loss) and its sister drug, Wegovy (which is prescribed as an anti-obesity treatment), use the same medication, semaglutide

Ancillary analysis We used metformin as a control in the secondary analysis

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