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Safety assessments in various animal models revealed no significant toxicity or adverse impact on physiological markers (Fawcett 2010)

J Am Heart Assoc 11(19):e026728 Wang J, Fan S, Xiong Q, Niu Y, Zhang X, Qin J, Shi Y, Zhang L (2021) Glucagon-like peptide-1 attenuates cardiac hypertrophy via the AngII/AT1R/ACE2 and AMPK/mTOR/p70S6K pathways

Magnesium glycinate helps to relax the body to aid in sleep quality, while some research has shown that glycine may improve sleep quality and cognitive function

Generally, surrogate endpoints are expected to predict clinical benefits

This anti-apoptotic mechanism is mediated through JAK/STAT signaling pathway activation (179)