After three weeks, women who received zinc supplements saw significant increases in IGF-1, but only if they were low in it at the start of the study
Though recent studies show this may not be true, the belief led to the development of agents to overcome GLP-1 deficiencies [19]
Although the majority of medications work this way, GLP-1s dont
A study published in Circulation noted that while these reductions in muscle volume appear proportionate to the weight loss achieved, the concern remains that excessive lean mass loss could lead to sarcopenia, reduced metabolic rate, and poorer long-term outcomes
(20) The control group experienced four times more BMC loss compared to the liraglutide group, with an approximate difference of 27g (95% CI: 5-48, p=.01)