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GLP-1 helps trigger insulin release from the pancreas, blocks glucagon secretion (which raises blood sugar levels), slows stomach emptying, and increases the feeling of fullness after eating

Discontinuation Rates Discontinuation rates due to adverse events in the Phase 2 trial were dose-dependent, ranging from approximately 6% in the 1 mg arm to 16% in the 12 mg arm

the step or linear pH gradient for the cation exchange chromatography process goes from a lower to a higher pH