n-acetylcysteine glutathione heavy metal detox mercury Detoxification Considerations Heavy Metal Detox Guides -

In: Hermanson GT, editor

doi: 10.1007/978-981-10-5311-5_20

In a recent study by Fiore et al., inhibition of IDO1 sensitized cancer cells to ferroptosis, leading to increased cell death in vitro and reduced tumor growth in vivo ( Inhibition of IDO1 and TDO2: a promising therapeutic strategy The failure of single-agent IDO1 inhibitors, such as epacadostat, in clinical trials highlighted the limitations of targeting a single enzyme in the kynurenine pathway ( Table 1 )

Acta 1558 , 113 (2002)

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