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While these drugs can aid weight loss, it is most effective when used in conjunction with healthy eating habits and regular physical activity
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1 Introduction Obesity is a prevalent and complex condition that significantly contributes to morbidity and mortality worldwide ( However, the psychological impact of tirzepatide, particularly its potential association with mental health outcomes, remains underexplored
doi:10.1136/tsaco-2018-000219
Previous studies have shown that selective depletion of synovial macrophages during experimental OA largely reduces cartilage damage and osteophyte formation, which are two major hallmarks of OA 48
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