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Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice
Statistical significance was determined by multiple two-tailed unpaired t -tests with correction for multiple comparisons using the Holm-dk method
141 These findings reveal a new redox regulation of NAD + by SIRT3dependent deacetylation in response to oxidative stress, improving the resistance to the detrimental effects of oxidative damage
While metformin has long served as the standard first-line therapy, many clinicians are now reconsidering whether a metformin-first and wait strategy is enough for this higher-risk population
Metabolic outcomes of elderly patient populations initiating exenatide BID versus insulin glargine in an ambulatory care setting
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