Like methionine, choline helps prevent fat from accumulating in the liver and supports its proper elimination
The participants included folks with cancer, liver disease, kidney diseases, and who were older adults and critically ill
However, for patients without a true vitamin B12 deficiency, research shows that B12 injections are unlikely to boost energy or reduce fatigue
Within the research community, NNMT inhibition is studied in pre-clinical models for its relationship to the NAD+ salvage pathway, methyl-donor homeostasis, and adipocyte energy metabolism
This enzyme plays a role in regulating NAD+ , a molecule essential for cellular energy, metabolic function, and overall cellular health